ISSN 1662-4009 (online)

ey0015.10-3 | Aetiology and heterogeneity of type 1 diabetes | ESPEYB15

10.3 Frequency and phenotype of T1DM in the first six decades of life: a cross-sectional, genetically stratified survival analysis from UK Biobank

NJ Thomas , SE Jones , MN Weedon , BM Shields , RA Oram , AT Hattersley

To read the full abstract: Lancet Diabetes Endocrinol. 2018;6:122-129T1DM formerly called juvenile or insulin dependent diabetes has so far been considered to be a disease of children adolescents and young adults according to traditional teaching. LADA or late autoimmune diabetes of the adult is known since several decades, however the older the patient with new onset diabetes the more li...

ey0015.10-13 | Comorbidities – short and long-term complications | ESPEYB15

10.13 Prevalence of celiac disease in 52,721 youth with T1DM: international comparison across three continents

ME Craig , N Prinz , CT Boyle , FM Campbell , TW Jones , SE Hofer , JH Simmons , N Holman , E Tham , E Fröhlich-Reiterer , S DuBose , H Thornton , B King , DM Maahs , RW Holl , JT Warner

To read the full abstract: Diabetes Care. 2017;40:1034-1040Researchers from The Children’s Hospital at Westmead, Sydney, Australia as well as scientists from institutions from three different continents, America, Europe and Australia have combined their data from large diabetes registries in order to: examine the prevalence of celiac disease (CD) in populations of patients with T1DM; investigat...

ey0016.1-1 | (1) | ESPEYB16

1.1. Genome-wide association analyses of chronotype in 697, 828 individuals provides insights into circadian rhythms

SE Jones , JM Lane , AR Wood , VT van Hees , J Tyrrell , RN Beaumont , AR Jeffries , HS Dashti , M Hillsdon , KS Ruth , MA Tuke , H Yaghootkar , SA Sharp , Y Jie , WD Thompson , JW Harrison , A Dawes , EM Byrne , H Tiemeier , KV Allebrandt , J Bowden , DW Ray , RM Freathy , A Murray , DR Mazzotti , PR Gehrman , DA Lawlor , TM Frayling , MK Rutter , DA Hinds , R Saxena , MN Weedon

To read the full abstract: Nat Commun 2019;10:343This paper reports many loci associated with chronotype (i.e. being a ‘morning person’ or ‘evening person’) in a genome-wide association study (GWAS) of 697, 828 participants from the UK Biobank and 23andMe cohorts. The link between chronotype and sleep timing and quality is well known. It was therefore interestin...